ExoTherapy: A proprietary platform for developing exosome-Based therapies
Exosome
API
Active Pharmaceutical Ingredient
nanodrug
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NurExone chose to base its ultimate drug delivery platform on exosomes-nanosized extracellular vesicles-due to their natural ability to reach inflamed or damaged tissue. By loading exosomes with therapeutic compounds, nanodrugs are created having natural regenerative properties and therapeutic impact.
ExoTherapy Benefits
Minimally invasive drug administration
The natural affinity of exosomes to inflamed or damaged tissue allows minimally invasive and targeted delivery of therapeutic molecules
Off the shelf
Ease of production, distribution and point of care administration
Cell-free
No patient personalization and minimal immunogenicity
Crosses the blood-brain-barrier
For neuron regeneration, rewiring and recovery
Possible Future Indications
Potential for licensing or collaboration agreements
with big pharma companies for:
- Approved or under-development drugs that cannot currently be delivered to the brain because they can’t cross the blood-brain-barrier
- Repurpose of products in low dosing or safer manner (nanoparticles that can penetrate cells)
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Biological or stem cell delivery to achieve a synergistic effect
◦ Inteligex collaboration for chronic SCI underway (received European Eureka grant funding)