General Description
photo-of-person-using-wheelchair NEW

General Description

Neuronal damage in general and SCI in particular involves a long and complex cascade of secondary events following the injury itself. The complexity of the cascade can affect the efficiency of the suggested treatments and there remains an unmet need for development of additional safe, efficient and convenient methods for treating SCI.

The new approach to SCI treatment is based on the view that intranasal exosome administration has broad potential and offers an alternative to other treatments cell transplantation that are under development to treat SCI.

Extensive research, conducted at Prof. Shulamit Levenberg’s lab at the Technion, Haifa in collaboration with Prof. Danny Offen from Tel Aviv University tested a novel proprietary treatment using intranasal administration of Exosomes driven from mesenchymal stem cells loaded with PTEN siRNA targeting complete spinal cord lesion in rats and enabled significant functional recovery.