EXOPTEN: CNSI

ExoPTEN: Central Nervous System Injuries

Regenerate. Rewire. Recover

Our Approach:

A Regenerative Approach to CNS Injury

ExoPTEN is NurExone’s lead nanodrug candidate for multiple high-impact Central Nervous System injuries and the first therapy being developed using our ExoTherapy platform.

Born from research at Israel’s Technion and Tel Aviv University, ExoPTEN uses exosomes loaded with a proprietary siRNA sequence designed to target PTEN, a key regulator of nerve regeneration. In preclinical studies, ExoPTEN has demonstrated nerve regeneration, neuroprotection and functional improvement following a short, minimally invasive treatment cycle.

ExoPTEN reflects NurExone’s core approach: using the body’s natural delivery system to advance targeted, minimally invasive regenerative medicine for central nervous system injury.

Some injuries heal naturally.
Others need a new approach.

ExoPTEN is being developed to address the limited regenerative capacity of the central nervous system.

Reversible Damage

Peripheral Tissues and Nerves

Peripheral tissues often activate a fast, natural repair response after minor injury. This is why everyday damage, like a scraped knee, will usually heal quickly with little or no treatment.

Irreversible Damage

Central Nervous System

Limited natural regeneration. Treatment is largely supportive and focused on symptom management.

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